Authors:

Huaixiu Wang

Shanxi Provincal Hospital, Taiyuan, Shanxi Province, China

Abstract:

Objective: To investigate the effect of Eupalinolide B (EB) on amyotrophic lateral sclerosis (ALS).
Method: EB was administered 20 mg/d orally for one month. Muscular tension,muscular strength and neural reflexes etc.before and after experiment were compared.
Results: After EB administration the abnormally lower muscular tension and muscular strength
were improved. Ankle clonus disappeared. Amyotrophic lateral sclerosis function rating system revised (ALSFRS-R) stopped worsening. But 10 days after discontinuation of EB, the above improvements disappeared gradually.
Discussion: EB might be effective on ALS and deserves further investigation

Keywords:

Eupalinolide B; amyotrophic lateral sclerosis; sesquiterpenes, Eupatorium Lindleyanum, Chinese herbs.

Citation:

Huaixiu Wang. The Effect of Eupalinolide B on AmyotrophicLateral Sclerosis : A Case Report. World Journal of Medical Oncology 2023