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Endometrial Serous Adenocarcinoma andPerineal Leiomyosarcoma: A rare case reportof Synchronous Primaries


Ebinesh A

Professor of Oral Medicine, Periodontology and Diagnosis, Faculty of Dental Medicine for girls, AlAzhar University, Cairo, Egypt, Misr International University, Cairo, Egypt.

Correspondence to Author: Ebinesh A


Background : The simultaneous presentation of endometrial carcinoma and perineal leiomyosarcoma in a patient as a synchronous tumor is very rare.
Case presentation : We describe a case of a 70-year-old postmenopausal lady who presented with post menopausal bleeding. On MR imaging, the patient had multiple irregular nodular polypoidal lesions arising from the endometrium along with another well-defined lobulated and encapsulated lesion in the perineum. Patient then underwent hysterectomy followed by histopathological examination which revealed coexisting serous type endometrial carcinoma and perineal leiomyosarcoma.
Conclusions : This case report describes this uncommon and interesting association of two rare entities with imaging features and histopathology. Despite its rarity, synchronous primary tumors in the female genital tract exist, and diagnosis and staging of both tumors preoperatively are largely beneficial


Ebinesh A. Endometrial Serous Adenocarcinoma and Perineal Leiomyosarcoma: A rare case report of Synchronous Primaries. World Journal of Medical Oncology 2023.

Journal Info

  • Journal Name: World Journal of Medical Oncology
  • Impact Factor: 2.709**
  • ISSN: 2766-6077
  • DOI: 10.52338/wjoncgy
  • Short Name: WJMOY
  • Acceptance rate: 55%
  • Volume: 6 (2024)
  • Submission to acceptance: 25 days
  • Acceptance to publication: 10 days


  • Crossref indexed journal impact factor of 2.980**
  • Publons indexed journal impact factor of 3.90**
  • Pubmed-indexed journal impact factor of 5.2**
  • International Scientific Indexing (ISI)-indexed journal impact factor of 2.980**
  • Eurasian Scientific Journal Index (ESJI) index journal impact factor of 2.980**
  • Semantic Scholar indexed journal impact factor of 2.980**
  • Cosmos indexed journal impact factor of 3.981**


  • International Reach
  • Peer Review
  • Rapid Publication
  • Open Access
  • High Visibility