Correspondence to Author: Shahab Rafieian, 

Department of thoracic surgery,Valiasr Hospital, Tehran university of medical science, Iran

Abstract:

Cancer metastasis, definded because the unfold of cancer cells to distant organs, accounts for several cancer-related deaths. Migration is one among several factors involved during this development. Mechanisms controling directional cancer invasion don’t seem to be absolutely understood. Endogenous electrical fields (EFs) are incontestible to be a very important steerage cue controling directional cell migration. Indeed, many sorts of cancer cells migrate directionally in associate degree EF. Understanding the electrical management of cancer invasion can facilitate develop noval approaches to forestall cancer metastasis.

Introduction: For multiple sorts of cancer, the most important reason for death is that the development of pathological process diseases[1]. Metastasis could be a multistep method wherever cancer cells invade close tissues and blood vessels, and establish secondary tumors in distant organs[2]. In detail, these steps embody native invasion, hurt, survival within the circulation, extravasations, and organization. The mechanisms of metastasis don’t seem to be absolutely understood. numerous environmental factors, together with cytokines and growth factors from autocrine and paracrine sources, are incontestible to stimulate neoplastic cell migration by making chemo maneuver signals[3].Aside from those usually identified chemical steerage, the endogenous electrical fields (EFs) has conjointly been tested to be a very important directional cue for directional cell migration.

Citation:

Shahab Rafieian. Electrical management of Cancer Breach: A Mini Review. World Journal of Medical Oncology 2020.