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Cancer Progression connected with Tumor-associated Macrophages

Correspondence to Author: Fischer Mahir, PhD 

Institute of Spatial Planning, University of Natural Resources and Life Sciences, Vienna, Austria


Tumor-associated macrophages area unit one amongst the most populations of inflammatory cells in cancers that favor neoplasm cell growth and survival. Tumor-derived factors like VEGF-A and CSF-1 recruit the macrophages in neoplasm small setting and alter their makeup in money supply to money supply or tumor-associated macrophages by secretion of many cytokines together with IL-4, IL-13 and VEGF-A. reciprocally tumor-associated macrophages free growth factors and protein that helps in neoplastic cell proliferation and metastasis. Tumor-associated phagocyte secreted cytokines promotes the growing and lymphangiogenesis that assist neoplasm cell to metastasise in distant organs. significantly, neoplasm-associated macrophages promote Associate in Nursing immunological disorder setting with the assistance of alternative immune cells within the tumor-bearing host that helps tumor to grow unbridled and unquestionable. additionally, neoplasm-associated macrophages induce resistance against cancer medical care and boost tumor regrowth once medical care. during this review, we tend to discuss the role of tumor-associated macrophages within the pathobiology of cancer. Understanding of the crucial role of tumor-associated macrophages in cancer progression could facilitate to assess potential therapeutic ways.


Tumor-associated Macrophages, Cancer Progression, Therapy Resistance, Immune Suppression


Fischer Mahir, PhD. Cancer Progression connected with Tumor-associated Macrophages. World Journal of Medical Oncology 2020.

Journal Info

  • Journal Name: World Journal of Medical Oncology
  • Impact Factor: 2.709**
  • ISSN: 2766-6077
  • DOI: 10.52338/wjoncgy
  • Short Name: WJMOY
  • Acceptance rate: 55%
  • Volume: 6 (2024)
  • Submission to acceptance: 25 days
  • Acceptance to publication: 10 days


  • Crossref indexed journal impact factor of 2.980**
  • Publons indexed journal impact factor of 3.90**
  • Pubmed-indexed journal impact factor of 5.2**
  • International Scientific Indexing (ISI)-indexed journal impact factor of 2.980**
  • Eurasian Scientific Journal Index (ESJI) index journal impact factor of 2.980**
  • Semantic Scholar indexed journal impact factor of 2.980**
  • Cosmos indexed journal impact factor of 3.981**


  • International Reach
  • Peer Review
  • Rapid Publication
  • Open Access
  • High Visibility